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Physicochemical Characterization of Airborne Particulate Matter in Medellín, Colombia, and its Use in an In Silico Study of Ventricular Action Potential

dc.creatorZapata-Hernandez C.
dc.creatorDurango-Giraldo G.
dc.creatorTobón C.
dc.creatorBuitrago-Sierra R.
dc.date2020
dc.date.accessioned2021-02-05T14:58:28Z
dc.date.available2021-02-05T14:58:28Z
dc.identifier.issn496979
dc.identifier.urihttp://hdl.handle.net/11407/5992
dc.descriptionParticulate matter (PM) is a complex mixture of particles that changes over time and from place to place; however, most PM is caused by the fuel combustion of motor vehicles and industry. PM is associated with acute and chronic illnesses, such as pulmonary and cardiovascular diseases. Medellín is one of the most polluted cities in Latin America. Therefore, the physicochemical characterization of its PM is necessary to understand its composition and effect on human health. In this study, PM was characterized by scanning electron microscopy (SEM), energy dispersive x-ray spectroscopy (EDS) analysis, Fourier infrared spectroscopy (FTIR), inductivity-coupled plasma optical emission spectrometry (ICP-OES), and thermogravimetric analysis (TGA) in order to evaluate its morphology and chemical composition. The SEM of the PM exhibited primary particles and agglomerates. The size of the particles ranged between 0.056 and 4.5 μm. The EDS revealed elements such as carbon, silicon, calcium, lead, and iron. Furthermore, carbon monoxide, carbon dioxide, and carbonyl and aliphatic functional groups were observed by means of FTIR. Additionally, weight losses associated with volatile matter and elemental carbon were identified in the TGA analysis. The TGA and FTIR confirmed the presence of fuel and lubricant traces. Subsequently, lead was selected among the most common components in the PM in order to conduct an in silico study into its effect on ventricular activity. Lead showed a pro-arrhythmic effect by shortening the duration of the action potential under normal electrophysiological conditions, which could be associated with cardiovascular diseases. © 2020, Springer Nature Switzerland AG.
dc.language.isoeng
dc.publisherSpringer Science and Business Media Deutschland GmbH
dc.relation.isversionofhttps://www.scopus.com/inward/record.uri?eid=2-s2.0-85091723868&doi=10.1007%2fs11270-020-04884-5&partnerID=40&md5=5ca695496e211a2dc0083713d70cd486
dc.sourceWater, Air, and Soil Pollution
dc.subjectAir pollutionspa
dc.subjectComputer simulationspa
dc.subjectHeart diseasesspa
dc.subjectParticulate matter compositionspa
dc.titlePhysicochemical Characterization of Airborne Particulate Matter in Medellín, Colombia, and its Use in an In Silico Study of Ventricular Action Potential
dc.typeArticleeng
dc.rights.accessrightsinfo:eu-repo/semantics/restrictedAccess
dc.identifier.doi10.1007/s11270-020-04884-5
dc.subject.keywordCarbon dioxideeng
dc.subject.keywordCarbon monoxideeng
dc.subject.keywordCardiologyeng
dc.subject.keywordChemical analysiseng
dc.subject.keywordDiseaseseng
dc.subject.keywordElectrophysiologyeng
dc.subject.keywordEnergy dispersive spectroscopyeng
dc.subject.keywordFourier transform infrared spectroscopyeng
dc.subject.keywordFuelseng
dc.subject.keywordOptical emission spectroscopyeng
dc.subject.keywordParticle size analysiseng
dc.subject.keywordParticles (particulate matter)eng
dc.subject.keywordScanning electron microscopyeng
dc.subject.keywordAirborne particulate matterseng
dc.subject.keywordCardio-vascular diseaseeng
dc.subject.keywordChemical compositionseng
dc.subject.keywordEnergy dispersive X ray spectroscopyeng
dc.subject.keywordOptical emission spectrometryeng
dc.subject.keywordParticulate Mattereng
dc.subject.keywordPhysico-chemical characterizationeng
dc.subject.keywordVentricular activityeng
dc.subject.keywordThermogravimetric analysiseng
dc.relation.citationvolume231
dc.relation.citationissue10
dc.publisher.facultyFacultad de Ciencias Básicasspa
dc.affiliationZapata-Hernandez, C., MATyER, Facultad de Ingeniería, Instituto Tecnológico Metropolitano, Cll. 54 A, Medellín, #30-01, Colombia
dc.affiliationDurango-Giraldo, G., MATyER, Facultad de Ingeniería, Instituto Tecnológico Metropolitano, Cll. 54 A, Medellín, #30-01, Colombia
dc.affiliationTobón, C., MATBIOM, Facultad de Ciencias Básicas, Universidad de Medellín, Cra. 87, Medellín, #30-65, Colombia
dc.affiliationBuitrago-Sierra, R., MATyER, Facultad de Ingeniería, Instituto Tecnológico Metropolitano, Cll. 54 A, Medellín, #30-01, Colombia
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